Elevate

Elevate – Advanced Activated Folate (5-MTHF) for Brain, Mood & Methylation Support*

High-Bioavailability Folate for Mental Health, Genetic Support & Cellular Function

Elevate features Quatrefolic®, a patented, highly bioavailable form of folate (vitamin B9) that delivers 5-methyltetrahydrofolate (5-MTHF) the active form your body and brain can use immediately.* This formula is designed to support healthy methylation, neurotransmitter production, and overall mental wellness, especially in individuals with MTHFR genetic variations.

Benefits of Elevate

• Supports healthy brain function and mood*

• Supports methylation and cellular function*

• Helps maintain healthy homocysteine metabolism*

• Supports neurotransmitter production, including serotonin, dopamine, and norepinephrine*

• Ideal for individuals with MTHFR polymorphisms*

Why Choose Elevate?

Folic acid and dietary folate must be converted by the MTHFR enzyme into 5-MTHF before the body can use them. Many individuals have genetic variations that reduce this conversion efficiency.

Elevate bypasses this step entirely by providing folate in its already active form, helping improve folate status without relying on MTHFR enzyme activity.*

Key Ingredient: Quatrefolic® (Activated Folate)

Quatrefolic® is a patented glucosamine salt of (6S)-5-MTHF that offers:

• Significantly higher bioavailability than folic acid*

• Greater stability and absorption than calcium salt forms of 5-MTHF*

• Faster and higher increases in plasma folate levels*

Research shows Quatrefolic® is:

• Up to 7 times more bioavailable than folic acid*

• More effective at raising blood folate levels in individuals with common MTHFR gene variants*

• Better absorbed than both folic acid and other 5-MTHF forms*

MTHFR Polymorphism & Methylation Support

The active folate form, 5-MTHF, plays a critical role in:

• Producing S-adenosylmethionine (SAMe), the body’s primary methyl donor

• Supporting DNA, protein, and neurotransmitter methylation*

• Converting homocysteine into methionine*

Individuals with reduced MTHFR function may struggle to maintain adequate 5-MTHF levels, making activated folate supplementation especially important*.

Brain Health & Mood Support

Low levels of 5-MTHF have been associated with altered neurotransmitter balance and increased risk of mood disorders.* Activated folate supports the production of key brain chemicals involved in mood, motivation, and emotional regulation.*

Clinical research suggests supplementation with 5-MTHF may be beneficial as nutritional support for individuals with depressive disorders, including those using antidepressant medications.*

Advanced Quality & Extended Release Design

Elevate is formulated to meet USP dissolution and disintegration standards for delayed-release dosage forms. This helps support consistent absorption and sustained folate availability.

• USP-grade excipients

• Designed for optimal stability and bioavailability

• Manufactured to meet or exceed cGMP quality standards

Who May Benefit from Elevate?

• Individuals with MTHFR gene variations

• Those seeking brain and mood support

• Individuals with low folate levels despite folic acid use

• People looking for a non–B12-masking folate option

• Anyone needing advanced methylation support*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.